The tunica media comprises a single layer of endothelial cells supported by a basement membrane. Intimal thickening can be circumferential or focal. It is caused by: (1) hyperplasia, (2) Intimal fibrosis or (3) oedema.
Intimal thickening can result in narrowing of the lumen, and in extreme cases, luminal occlusion.
This image shows asymmetrical intimal thickening. On high power, the intima has a loosely, oedematous appearance. The lumen is narrowed by >50%.
This project is funded by Leeds Hospital Charity and The Pathological Society of Great Britain and Ireland. All whole slide images are hosted on the Leeds Virtual Pathology website and we are grateful for their collaboration.
Further information on our funder and collaborators can be found here:
Leeds Hospital Charity: www.leedshospitalscharity.org.uk
The Pathological Society of Great Britain and Ireland: www.pathsoc.org
Leeds Virtual Pathology website: www.virtualpathology.leeds.ac.uk
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